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Document 3214
DOCN M94A3214
TI Opportunistic infections in HIV-2 infected patients in Dakar (Senegal).
DT 9412
AU Sow PS; Faye MA; Diouf G; Coll-Seck AM; Infectious Diseases Department,
Fann Hospital, Dakar.
SO Int Conf AIDS. 1994 Aug 7-12;10(1):127 (abstract no. PA0128). Unique
Identifier : AIDSLINE ICA10/94369361
AB OBJECTIVES: (1) To identify the opportunistic infections in HIV-2
infected patients in Dakar. (2) To compare clinical manifestations in
HIV-2 infected patients with HIV-1. METHODOLOGY: It is a case-control
study from January 1986 to June 1993. Inclusion criteria were: patients
with manifestations of HIV infection according to the clinical Bangui
classification (WHO 1985) and serology positive in Western-blot.
RESULTS: 181 HIV-1 and 58 HIV-2 infected patients were enrolled in this
study. The mean age of HIV-2 and HIV-1 infected patients is 39 years +/-
9.95 (SD) and 33 years +/- 9.17 (SD) respectively. The sex-ratio
(male/female) is 3.2 for HIV-2 and 2.0 for HIV-1. Opportunistic
infections in these patients were: tuberculosis (HIV-2: 24.1%, HIV-1:
39.7%, p < 0.05); chronic diarrhea (HIV-2: 74.1%, HIV-1: 63.5%, p =
0.15); oral candidasis (HIV-2: 79.3%, HIV-1: 87.8%, p = 0.10); atypical
pneumonia (HIV-2: 31%, HIV-1: 29.8%, p = 0.92); Kaposi sarcoma (HIV-2:
5.1%, HIV-1: 5.5%, p = 0.90); Herpes zoster (HIV-2: 1.7%, HIV-1: 5.5%, p
= 0.20). CONCLUSION: The classic opportunistic infections in HIV-1
patients are also seen in HIV-2 patients at the stage of AIDS. Only
tuberculosis is more frequently seen in HIV-1 than HIV-2 patients. HIV-2
is not less lisky for opportunistic infections than HIV-1 at the stage
of AIDS.
DE Acquired Immunodeficiency Syndrome/COMPLICATIONS Adult AIDS-Related
Opportunistic Infections/*CLASSIFICATION/ EPIDEMIOLOGY Candidiasis,
Oral/EPIDEMIOLOGY Case-Control Studies Chronic Disease Comparative
Study Diarrhea/EPIDEMIOLOGY Female Herpes Zoster/EPIDEMIOLOGY Human
*HIV-1 *HIV-2 Male Pneumonia/EPIDEMIOLOGY Risk Factors Sarcoma,
Kaposi's/EPIDEMIOLOGY Senegal Tuberculosis/EPIDEMIOLOGY MEETING
ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).